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Proteome analysis related to unsaturated fatty acid synthesis by interfering bovine adipocyte ACSL1 gene

ABSTRACT: Unsaturated fatty acids (UFAs) in beef are essential for human health. Long-chain fatty acyl-CoA synthase 1 (ACSL1) is a crucial gene for UFAs synthesis in bovine adipocytes. To assess the protein expression profile during UFAs synthesis, we performed a proteomic analysis of bovine adipocytes by RNA interference and non-interference with ACSL1 using label-free techniques.

ORGANISM(S): Bos Taurus

SUBMITTER: Yuzhu Luo

PROVIDER: PXD050702 | iProX | Fri Mar 15 00:00:00 GMT 2024

REPOSITORIES: iProX

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Proteome Analysis Related to Unsaturated Fatty Acid Synthesis by Interfering with Bovine Adipocyte <i>ACSL1</i> Gene.

Bai Yanbin Y Li Jingsheng J Wei Yali Y Chen Zongchang Z Liu Zhanxin Z Guo Dashan D Jia Xue X Niu Yanmei Y Shi Bingang B Zhang Xiaolan X Zhao Zhidong Z Hu Jiang J Han Xiangmin X Wang Jiqing J Liu Xiu X Li Shaobin S

Antioxidants (Basel, Switzerland) 20240524 6

Unsaturated fatty acids (UFAs) in beef play a vital role in promoting human health. Long-chain fatty acyl-CoA synthase 1 (ACSL1) is a crucial gene for UFA synthesis in bovine adipocytes. To investigate the protein expression profile during UFA synthesis, we performed a proteomic analysis of bovine adipocytes by RNA interference and non-interference with <i>ACSL1</i> using label-free techniques. A total of 3558 proteins were identified in both the NC and si-treated groups, of which 1428 were diff ...[more]

PMID: 38929080

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