Dataset Information

Comprehensive mass spectral libraries of human thyroid tissue and cells

ABSTRACT: We established deep-coverage thyroid-specific spectral libraries encompassing over 12,000 proteins, including samples from nine types of thyroid primary and lymph node metastases tissues and fifty thyroid cancer cell lines.

ORGANISM(S): Homo Sapiens

SUBMITTER: Tiannan Guo

PROVIDER: PXD051051 | iProX | Fri Sep 27 00:00:00 BST 2024

REPOSITORIES: iProX

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Publications

Comprehensive Mass Spectral Libraries of Human Thyroid Tissues and Cells.

Li Lu L Jiang Wenhao W Wei Wenjun W Krishnamoorthy Gnana P GP Hu Pingping P Chen Mengni M Tiedje Vera V Acuña-Ruiz Adrián A Wang He H Wang Zhihong Z Wang Jianbiao J Liu Hanqing H Chen Wanyuan W Guan Haixia H Chen Chuang C Zhang Hao H Wang Yu Y Fagin James A JA Guo Tiannan T Zhu Yi Y Wang Yingrui Y Gao Jianqing J Sun Yaoting Y

Scientific data 20241228 1

Thyroid nodules are a common endocrine condition with an increasing incidence over the decades. Data-independent acquisition has been widely utilized in discovery proteomics to identify disease biomarkers and therapeutic targets. To analyze the thyroid disease-related proteome in a high-throughput, reproducible and reliable manner, we introduce thyroid-specific peptide spectral libraries. Here, we generated four deep-coverage libraries through four mass spectrometers comprising Q Exactive HF, Or ...[more]

PMID: 39732735

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Dataset Information

Comprehensive mass spectral libraries of human thyroid tissue and cells

Publications

Comprehensive Mass Spectral Libraries of Human Thyroid Tissues and Cells.

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