Tunable activated esters for lysine labeling in proteome

ABSTRACT: The development of various heteroaromatic activated esters designed for selective lysine labeling within the proteome for profiling purposes. Through systematic optimization of the reactivity and selectivity of these esters, we identified a series of effective probe molecules suitable for both in vitro and cellular applications. These findings are of considerable importance for enhancing our comprehension of protein functionalities and mechanisms, facilitated by the precise identification and analysis of protein labeling and profiling.

ORGANISM(S): Homo Sapiens

SUBMITTER: Rui Wang  

PROVIDER: PXD051323 | iProX | Tue Apr 09 00:00:00 GMT+01:00 2024

REPOSITORIES: iProX