Quantative pTyr protein complex

ABSTRACT: Our current research focuses on the complex-centric quantification of pTyr protein complexes. We initially constructed a tri-functional probe based on pTyr superbinder (SH2-S) for the enrichment of pTyr protein complexes. The pTyr protein complexes were separated by ion exchange chromatography (IEC). To further quantify the complexes, we developed an algorithm for co-fractionation/mass spectrometry (CF/MS) protein complex screening and quantification.

ORGANISM(S): Homo Sapiens

SUBMITTER: Mingxia Gao  

PROVIDER: PXD052742 | iProX | Fri May 31 00:00:00 BST 2024

REPOSITORIES: iProX