Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Proteomic analysis of human Wharton's jelly mesenchymal stem cells and human amniotic epithelial stem cells: a comparison of therapeutic potential

ABSTRACT: proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells

ORGANISM(S): Homo Sapiens

SUBMITTER: Luyang Yu

PROVIDER: PXD052844 | iProX | Wed Jun 05 00:00:00 BST 2024

REPOSITORIES: iProX

ACCESS DATA

Json Xml

Publications

Proteomic analysis of human Wharton's jelly mesenchymal stem/stromal cells and human amniotic epithelial stem cells: a comparison of therapeutic potential.

Ge Zhen Z Qiu Chen C Zhou Jiayi J Yang Zhuoheng Z Jiang Tuoying T Yuan Weixin W Yu Luyang L Li Jinying J

Scientific reports 20241114 1

Perinatal stem cells have prominent applications in cell therapy and regenerative medicine. Among them, human Wharton's jelly mesenchymal stem/stromal cells (hWJMSCs) and human amniotic epithelial stem cells (hAESCs) have been widely used. However, the distinction in the therapeutic potential of hWJMSCs and hAESCs is poorly understood. In this study, we reported the phenotypic differences between these two distinct cell types and provided the first systematic comparison of their therapeutic pote ...[more]

PMID: 39543366

Similar Datasets

Proteomic profiling of human mesenchymal stem cells derived from umbilical cord or adipose tissue

Project description:We performed a proteomic profiling of human mesenchymal stem cells (hMSCs) derived from adipose tissue or umbilical cord.

2018-07-11 | PXD009893 | Pride

Human umbilical cord blood-derived mesenchymal stem cells from 2 donors

Project description:screening of signature deterimes the individual variations in the therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells There is paucity of information whether human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) from separate donors might have different effects on improving myocardial repair after myocardial infarction (MI).

2011-02-19 | GSE27414 | GEO

Expression data from human Wharton's jelly stem cells

Project description:Human umbilical cord Wharton’s jelly stem cells (WHJSC) are gaining attention as a possible clinical source of mesenchymal stem cells for use in cell therapy and tissue engineering due to their high accessibility, expansion potential and plasticity. However, the cell viability changes that are associated to sequential cell passage of these cells are not known. In this analysis, we have identified the gene expression changes that are associated to cell passage in WHJSC. We used microarrays to detail the global programme of gene expression underlying cell passage on WHJSC.

2011-07-06 | GSE30391 | GEO

Proteomic Analysis of Umbilical Cord and Adult Mesenchymal Stem Cells

Project description:Shotgun proteomic analysis was performed on lysates from umbilical cord and adjult mesenchymal stem cells

2022-12-19 | PXD032994 | Pride

Gene expression of exosomes from human umbilical cord mesenchymal stem cells

Project description:To determine the gene expression of exosomes in human umbilical cord mesenchymal stem cells

2024-11-01 | GSE280447 | GEO

Human umbilical cord blood-derived mesenchymal stem cells from 2 donors

2011-02-19 | E-GEOD-27414 | biostudies-arrayexpress

Expression data from human Wharton's jelly stem cells

2011-07-06 | E-GEOD-30391 | biostudies-arrayexpress

Gene Expression Profile of Human Umbilical Cord Mesenchymal Stem Cells (hUC-MSCs) Culutured in Chemical Defined Serum Free Medium

Project description:Human umbilical cord mesenchymal stem cells maintained multipotency and immunosuppressive ability when being cultured in chemical defined serum free medium, but gained different gene expression profile. We used microarrays to identify the transcriptional difference between human umbilical cord mesenchymal stem cells cultured in serum containing medium and chemical defined serum free medium. human umbilical cord mesenchymal stem cells were cultured in conventional serum containing medium and chemical defined serum free medium separately. Total RNA was extracted and hybridized on Affymetrix microarrays.

2014-10-28 | E-GEOD-62665 | biostudies-arrayexpress

Expression data from human umbilical cord-derived mesenchymal stem cells

Project description:Mesenchymal stem cells (MSCs) have been shown to exert therapeutic effects on various autoimmune diseases. However, such therapeutic effect is not always achieved. Among many reasons, MSC culture methodologies may account for the these differences. It is known that oxygen concentration could profoundly affect the properties of MSCs. Therefore, we compared human umbilical cord derived MSCs cultured under hypoxic and normoxic conditions. We used microarrays to profile the gene expression of human umbilical cord derived MSCs under 10% oxygen and normoxia conditions.

2018-09-23 | GSE97773 | GEO

Epicardial transplantation of antioxidant polyurethane scaffold based human amniotic epithelial stem cell patch for myocardial infarction treatment

Project description:secretome proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells

2023-07-18 | PXD043861 |