A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer

ABSTRACT: Through chemical probe screening, we uncovered a novel mechanism of RNA splicing in paclitaxel-resistant TNBC and identified PRMTs as therapeutic targets.

ORGANISM(S): Homo Sapiens

SUBMITTER: Qin Wu  

PROVIDER: PXD053336 | iProX | Sat Jun 22 00:00:00 BST 2024

REPOSITORIES: iProX