In-depth Proteomics and Phosphoproteomics Reveal Biomarkers and Molecular Pathways of Chronic Intermittent Hypoxia in Mice

ABSTRACT: Obstructive sleep apnea (OSA) syndrome is characterized by Chronic Intermittent Hypoxia (CIH). In this study, we employed Data-independent acquisition (DIA) Mass Spectrometry to conduct comprehensive proteomic and phosphoproteomic profiling of a murine model subjected to Chronic Intermittent Hypoxia (CIH), a model we had previously established. Utilizing three CIH and three normal control genioglossus samples, we gathered valuable insights into the molecular alterations associated with CIH.

ORGANISM(S): Homo Sapiens

SUBMITTER: Qiang Li  

PROVIDER: PXD053746 | iProX | Mon Jul 08 00:00:00 GMT+01:00 2024

REPOSITORIES: iProX