P. micra surface protein TmpC interacts directly with OSCC cell lines via CKAP4
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ABSTRACT: P. micra surface protein TmpC interacts directly with OSCC cell lines via CKAP4, a receptor frequently overexpressed in human OSCC tumors. The interaction of TmpC and CKAP4 mediates bacterial attachment, invasion, and metastasis-promoting effects of P. micra on OSCC and subsequently activates HIF-1α and autophagy signaling, via CKAP4-RanBP2 and CKAP4-NBR1 interaction, respectively.
ORGANISM(S): Homo Sapiens
SUBMITTER:
Qiang Feng
PROVIDER: PXD054166 | iProX | Wed Jul 24 00:00:00 BST 2024
REPOSITORIES: iProX
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