Dataset Information

Snake (Elaphe taeniura) IgY was truncated at N338 of the IgY heavy chain constant region

ABSTRACT: One of our previous studies has shown that there are two IgY subclasses (termed IgY1 and IgY2) in the serum of snake Elaphe taeniura, and both subclasses are expressed as full-length and shortened isoforms (IgY1-L, IgY2-L,IgY1-S, and IgY2-S). Using 2-DE and LC-MS/MS, we detected IgY1-L, IgY2-L,IgY1-S, IgY2-S, and the trunction (IgY-T), the LC-MS/MS results showed both IgY1and IgY2 were truncted at N338 of the heavy chain constant region.

ORGANISM(S): Elaphe Taeniura

SUBMITTER: Ming Zhang

PROVIDER: PXD055127 | iProX | Fri Aug 23 00:00:00 GMT+01:00 2024

REPOSITORIES: iProX

ACCESS DATA

Publications

(D-Ala2)-Met-enkephalinamide: a potent, long-lasting synthetic pentapeptide analgesic.

Pert C B CB Pert A A Chang J K JK Fong B T BT

Science (New York, N.Y.) 19761001 4262

[D-Ala2]-Met-enkephalinamide (DALA), a synthetic enkephalin analog designed by in vitro analysis, binds to opiate receptors almost as tightly as methionine-enkephalin. Since it is not susceptible to degradation by brain enzymes, low doses (5 to 10 micrograms) cause profound, long-lasting, morphine-like analgesia when microinjected into rat brain. ...[more]

PMID: 968485

Similar Datasets

Project description:We used gene expression accompanied by physical characteristics and gill Na+/K+-ATPase activity to analyze physiological differences associated with two life history variations of juvenile fall Chinook Salmon in the Snake River basin. Subyearlings originating in the Snake River typically migrate seaward as subyearlings, whereas many subyearlings from the Clearwater River delay seaward migration during summer and complete seaward migration the following spring as yearlings. We examined gill Na+/K+-ATPase activity and gene expression of subyearlings at different times during rearing and seaward emigration. Natural-origin Snake River subyearlings rearing under an increasing photoperiod and seasonally increasing temperatures showed a typical increasing pattern of parr to smolt gill Na+/K+-ATPase activity development, which then declined into autumn. In contrast, Clearwater River subyearlings that had experienced cooler temperatures showed no pattern of increasing gill Na+/K+-ATPase activities and were not different from parr. Liver transcription of genes involved in DNA repair and binding, the cell cycle, metabolism (steroid, fatty acid and other metabolic pathways) iron homeostasis, heme and oxygen binding, the immune response, and male sexual development were enriched amongst genes differentially expressed between Snake River parr versus smolts. Gene expression results confirmed that Clearwater River subyearlings were parr-like in their physiological status. By autumn, subyearlings had low gill Na+/K+-ATPase activities despite their large size and external smolt characteristics. We suggest that environmental factors like temperature and photoperiod influence subyearling physiological status in each river that ultimately dictates juvenile life history pathways. Non-migrating and migrating natural subyearling fall Chinook salmon were collected from the Snake River. Non-migrating natural subyearling fall Chinook salmon were collected from the Clearwater River. Twelve fish were collected at each of four different time points for a total of 48 fish. Total RNA was extracted from the liver of each fish. Equal amounts of RNA from three fish were pooled to create four pools of RNA per time point. Each RNA pool was hybridized to an array for a total of 16 arrays with four arrays per time point.

Dataset Information

Snake (Elaphe taeniura) IgY was truncated at N338 of the IgY heavy chain constant region

Publications

(D-Ala2)-Met-enkephalinamide: a potent, long-lasting synthetic pentapeptide analgesic.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets