Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: Chunlin Gao
PROVIDER: PXD055324 | iProX | Sun Aug 25 00:00:00 BST 2024
REPOSITORIES: iProX
Journal of cachexia, sarcopenia and muscle 20250201 1
<h4>Background</h4>The presence of sarcopenia in patients with chronic kidney disease (CKD) is associated with poor prognosis. The mechanism underlying CKD-induced muscle wasting has not yet been fully explored. This study investigates the influence of renal secretions on muscles using multiomics sequencing.<h4>Methods</h4>The kidney transcriptome analysis by RNA-seq and protein profiling by tandem mass tag (TMT), serum TMT and muscle TMT were performed in CKD established using 0.2% adenine and ...[more]