OMe-Ph-Elemene treated colorectal cancer cells for proteomics sequencing
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Yong Xia
PROVIDER: PXD055327 | iProX | Sat Aug 24 00:00:00 BST 2024
REPOSITORIES: iProX
Publications
The Novel Elemene Derivative, OMe-Ph-Elemene, Attenuates Oxidative Phosphorylation and Facilitates Apoptosis by Inducing Intracellular Reactive Oxygen Species.
Guo Jianhua J Wang Jiayi J Fan Shuhao S Gao Mucong M Liu Guodu G Xia Yong Y
Antioxidants (Basel, Switzerland) 20241209 12
The incidence and mortality rates of colorectal cancer have been steadily increasing, making it one of the most prevalent cancers globally. Although current chemotherapy drugs have shown some efficacy in treating this disease, their associated side effects necessitate the development of more effective treatments and medications. The clinical application of elemene is widely utilized in tumor treatment; however, its efficacy is hindered by the requirement for high dosage and suboptimal anticancer ...[more]
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