Dataset Information
Proteomic analysis of EVs from human UCMSC
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Qingjian Ou
PROVIDER: PXD055465 | iProX | Mon Sep 02 00:00:00 BST 2024
REPOSITORIES: iProX
Publications
Clusterin-carrying extracellular vesicles derived from human umbilical cord mesenchymal stem cells restore the ovarian function of premature ovarian failure mice through activating the PI3K/AKT pathway.
Stem cell research & therapy 20240913 1
<h4>Background</h4>Emerging evidence has highlighted the therapeutic potential of human umbilical cord mesenchymal stem cells (UC-MSCs) in chemotherapy-induced premature ovarian failure (POF). This study was designed to investigate the appropriate timing and molecular mechanism of UC-MSCs treatment for chemotherapy-induced POF.<h4>Methods</h4>Ovarian structure and function of mice were assessed every 3 days after injections with cyclophosphamide (CTX) and busulfan (BUS). UC-MSCs and UC-MSCs-deri ...[more]
