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Analysis of phosphorylated proteins in ATP6V1G1 overexpressed hepatoma cells

ABSTRACT: To investigate the biological functions of ATP6V1G1 related proteins with overexpression and phosphorylation changes in hepatocellular carcinoma cells

ORGANISM(S): Homo Sapiens

SUBMITTER: Xue Qin

PROVIDER: PXD055721 | iProX | Mon Sep 09 00:00:00 BST 2024

REPOSITORIES: iProX

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Identification and validation of ATP6V1G1-regulated phosphorylated proteins in hepatocellular carcinoma.

Zhang Yi Y Lu Liuyi L Chen Mingxing M Nie Jiaqi J Qin Xue X Chen Huaping H

PloS one 20241202 12

V-ATPase Subunit G1 (ATP6V1G1) is one of the subunits of Vacuolar ATPases. Previous studies have indicated that ATP6V1G1 plays important roles in hepatocellular carcinoma (HCC) and is associated with HCC progression. However, the effect of ATP6V1G1 in HCC requires further elucidation. The aim of the present study was to explore the roles of ATP6V1G1 in HCC and further decipher the detailed mechanism. To identify the phosphorylated proteins regulated by ATP6V1G1 in HCC, phosphoproteomics and LC-M ...[more]

PMID: 39621600

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