Multi-Omics of Spinal Ependymal Tumor
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Wenqing Jia
PROVIDER: PXD056112 | iProX | Fri Sep 20 00:00:00 BST 2024
REPOSITORIES: iProX
Publications
Multi-omics analysis delineates molecular signatures of spinal ependymal tumor.
Liu Weihao W Ning Chao C Geng Xiaohan X Wang Bo B Zhang Yaowu Y Wang Chong C Liu Yixiang Y Zheng Guanghao G Wang Yongzhi Y Wang Xinyu X Li Dong D Jia Wenqing W
Cellular oncology (Dordrecht, Netherlands) 20251029 6
<h4>Background</h4>Spinal ependymal tumors are a diverse group of neoplasms encompassing four subtypes: spinal ependymoma (SP-EPN), spinal ependymoma, MYCN-amplification (SP-EPN-MYCN), spinal myxopapillary ependymoma (SP-MPE), and spinal subependymoma (SP-SE). However, the molecular differences among these subtypes remain largely unknown.<h4>Methods</h4>Using an integrated multi-omics approach (whole-genome sequencing, RNA-seq, and mass spectrometry), we identified the distinct molecular charact ...[more]
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