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Proteomic and phosphoproteomic landscape of kidney in rhesus macaques with SARS-CoV-2 infection

ABSTRACT: Six rhesus monkeys were divided into a control group (n=3) and a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection group (n=3). Meanwhile, their kidneys were further segmented into three regions: renal cortex (Cor), inner medulla (IM), and outer medulla (OM), and liquid chromatography-tandem mass spectrometry-based proteomics and phosphoproteomic profiling were conducted on these regions. Next, we conducted a comprehensive bioinformatics analysis, including differential analysis, functional enrichment, kinase prediction and potential drug target prediction.

ORGANISM(S): Macaca Mulatta

SUBMITTER: Juntao Yang

PROVIDER: PXD056118 | iProX | Mon Sep 23 00:00:00 BST 2024

REPOSITORIES: iProX

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