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HSGA glioma tissue and benign tissue in Huashan Hospital

ABSTRACT: HSGA glioma tissue and benign tissue in Huashan Hospital

ORGANISM(S): Homo Sapiens

SUBMITTER: Tiannan Guo

PROVIDER: PXD056311 | iProX | Fri Sep 27 00:00:00 BST 2024

REPOSITORIES: iProX

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Proteomic profiling of gliomas unveils immune and metabolism-driven subtypes with implications for anti-nucleotide metabolism therapy.

Zhang Jinsen J Sun Rui R Lyu Yingying Y Liu Chaxian C Liu Ying Y Feng Yuan Y Fu Minjie M Wong Peter Jih Cheng PJC Du Zunguo Z Qiu Tianming T Zhang Yi Y Zhuang Dongxiao D Qin Zhiyong Z Yao Yu Y Zhu Wei W Guo Tiannan T Hua Wei W Yang Hui H Mao Ying Y

Nature communications 20241119 1

Gliomas exhibit high heterogeneity and poor prognosis. Despite substantial progress has been made at the genomic and transcriptomic levels, comprehensive proteomic characterization and its implications remain largely unexplored. In this study, we perform proteomic profiling of gliomas using 343 formalin-fixed and paraffin-embedded tumor samples and 53 normal-appearing brain samples from 188 patients, integrating these data with genomic panel information and clinical outcomes. The proteomic analy ...[more]

PMID: 39562821

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