The influence of IL-1β and TNF-α on the tenogenic differentiation of human periodontal ligament stem cells via global proteomic analysis

ABSTRACT: The hPDLSCs were cultured in the tenogenic medium treated with 0.1 ng/ml IL-1β or 10 ng/ml TNF-α for 7 days. Total proteins were isolated from the collected cell samples. Subsequently, the LFQ-based proteomic analysis was conducted for the extracted proteins in each group as established procedures [59]. Differential expression analysis was performed by comparing the expression levels of the identified proteins in the hPDLSCs treated with IL-1β or TNF-α with those in the Ctrl group.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jialin Chen  

PROVIDER: PXD056585 | iProX | Sat Oct 05 00:00:00 GMT+01:00 2024

REPOSITORIES: iProX