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Decoding the Femoral and Tibial Entheses of the Human Anterior Cruciate Ligament

ABSTRACT: To analyze the location-specific graduated mineral composition and assembly, and mechanical transitions of the FE and TE in human knee joints.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xuesong Dai

PROVIDER: PXD056631 | iProX | Tue Oct 08 00:00:00 BST 2024

REPOSITORIES: iProX

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Decoding the mechanical characteristics of the human anterior cruciate ligament entheses through graduated mineralization interfaces.

Fang Jinghua J Wang Xiaozhao X Lai Huinan H Li Wenyue W Yao Xudong X Pan Zongyou Z Mao Renwei R Yan Yiyang Y Xie Chang C Lin Junxin J Sun Wei W Li Rui R Wang Jiajie J Dai Jiacheng J Xu Kaiwang K Yu Xinning X Xu Tengjing T Duan Wangping W Qian Jin J Ouyang Hongwei H Dai Xuesong X

Nature communications 20241026 1

The anterior cruciate ligament is anchored to the femur and tibia via specialized interfaces known as entheses. These play a critical role in ligament homeostasis and joint stability by transferring forces, varying in magnitude and direction between structurally and functionally dissimilar tissues. However, the precise structural and mechanical characteristics underlying the femoral and tibial entheses and their intricate interplay remain elusive. In this study, two thin-graduated mineralization ...[more]

PMID: 39462005

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