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Proteomic analysis of membrane vesicles of enterococcus faecalis under different pH conditions

ABSTRACT: we extracted and compared the protein compositions of membrane vesicles of enterococcus faecalis at pH 7.0 and pH 9.0.

ORGANISM(S): Enterococcus Faecalis Og1rf

SUBMITTER: Lihong Guo

PROVIDER: PXD056708 | iProX | Thu Oct 10 00:00:00 BST 2024

REPOSITORIES: iProX

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Membrane Vesicles of Enterococcus faecalis: In Vitro Composition Analysis and Macrophage Inflammatory Response Under Different pH Conditions.

Yuan Zijian Z Huang Wenling W Chan Poukei P Zhou Jiani J Liang Jingheng J Guo Lihong L

Microorganisms 20250610 6

Enterococcus faecalis (E. faecalis) is one of the most detected bacteria in persistent apical periodontitis (PAP), with alkaline tolerance enabling post-treatment survival. In this study, we will investigate how alkaline conditions alter proteomic and metabolomic profiles of E. faecalis membrane vesicles (MVs) and preliminarily investigate the role of MVs of E. faecalis in the regulation of macrophage inflammatory response. E. faecalis MVs were characterized us ...[more]

PMID: 40572231

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