Project description:Histone Methyltransferase G9a in Primary Sensory Neurons Promotes Inflammatory Pain and Transcription of Trpa1 and Trpv1 via Bivalent Histone Modifications

| PRJNA1137273 | ENA

ChIP-seq of Drosophila melanogaster plasmatocytes against various histone modifications

Project description:To identify the presence of different chromatin states in homogeneous primary cells, Drosophila melanogaster plasmatocytes were isolated from 3rd instar larvae and subjected to cross-linked ChIP-seq using antibodies against a range of H3 histone modifications and PolII.

2022-05-31 | E-MTAB-10707 | biostudies-arrayexpress

EpiProfile 2.0: a proteomics tool to quantify histone modifications by mass spectrometry

Project description:The histone LC-MS/MS data analysis is challenging due to the large number and variety of isobaric histone peptides, and the high dynamic range of histone peptide abundances. We introduce EpiProfile 2.0 to quantify histone post-translational modifications from mass spectrometry data, in which fragment ions are used to determine the retention time of peptides and discriminate isobaric peptides. EpiProfile can automatically recognize and efficiently process both data-dependent and data-independent acquisition runs (DDA and DIA), and high-resolution and low-resolution instrument runs. The proteomics tool was tested on human cells and validated by synthetic histone peptides. EpiProfile is the first automatic program to determine the retention time and discriminate isobaric peptides for histone modifications with DIA MS.

2018-05-29 | PXD004166 | Pride

Histone modifications regulated by HDAC5 in PDAC cells

Project description:Histone modifications regulated by HDAC5 in PDAC cells

| PRJNA627431 | ENA

Expression data of stimulated murine primary lung fibroblasts

Project description:Expression data of stimulated murine primary lung fibroblasts

| PRJNA657428 | ENA