RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Mingxia Yan
PROVIDER: PXD057090 | iProX | Wed Oct 23 00:00:00 BST 2024
REPOSITORIES: iProX
Publications
RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma.
Pan Hongyu H Liao Li L Xu Siwei S Xu Yujian Y Chai Wenjun W Liu Xiaoli X Li Jing J Cao Yue Y Sun Lei L Liu Qian Q Yan Mingxia M
Journal of translational medicine 20241225 1
<h4>Background</h4>Increased ribosome biogenesis is required for tumor growth. In this study, we investigated the function and underlying molecular mechanism of ribosome biogenesis factor (RBIS) in the progression of non-small cell lung cancer (NSCLC).<h4>Methods</h4>In our study, we conducted a comprehensive analysis to identify key genes implicated in ribosome biogenesis by leveraging a Gene Set Enrichment Analysis (GSEA) dataset. Subsequently, we performed a comparative analysis of gene expre ...[more]
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