Reconstitution of Pluripotency from Mouse Fibroblast through Sall4 Overexpression

ABSTRACT: We report that SALL4 alone, under an optimized reprogramming medium iCD4, is capable of reprogramming mouse fibroblasts into iPSCs. To identify SALL4-direct-interacting proteins, we performed immunoprecipitation followed by mass spectrometry (IP-MS) using MEFs overexpressing WT-SALL4 or SALL4 mutants (ΔZFC1, ΔZFC2, ΔZFC3, and ΔN12) at day 1.

ORGANISM(S): Mus Musculus

SUBMITTER: Jing Liu  

PROVIDER: PXD057516 | iProX | Tue Nov 05 00:00:00 GMT 2024

REPOSITORIES: iProX