Murine Leukemia Virus GlycoGag Antagonizes SERINC5 via the ER-phagy Receptor RETREG1

ABSTRACT: Our findings thus far indicate that Ser5 and glycoGag can be detected in the ER, with glycoGag downregulating Ser5 intracellularly through lysosomal degradation. We hypothesized that glycoGag downregulation of Ser5 is mediated by ER-phagy. Thus, we employed affinity-purified MS to identify its specific ER-phagy receptor.

ORGANISM(S): Homo Sapiens

SUBMITTER: Sunan Li  

PROVIDER: PXD057978 | iProX | Sun Nov 17 00:00:00 GMT 2024

REPOSITORIES: iProX