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Urinary metabolomics analysis based on LC-MS for diagnosis and monitoring of Acute coronary syndrome

ABSTRACT: Acute coronary syndrome (ACS) is a kind of cardiovascular disease caused by acute myocardial ischemia. The aim of this study was to use urine metabolomics to explore the potential biomarkers for the diagnosis of ACS and the changes in metabolites during the development of the disease.

ORGANISM(S): Homo Sapiens

SUBMITTER: Chengyan He

PROVIDER: PXD058501 | iProX | Tue Dec 03 00:00:00 GMT 2024

REPOSITORIES: iProX

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Urinary metabolomics analysis based on LC-MS for the diagnosis and monitoring of acute coronary syndrome.

Liu Jiaqi J Wang Aiwei A Qi Feng F Liu Xiaoyan X Guo Zhengguang Z Sun Haidan H Zhao Mindi M Li Tingmiao T Xue Fei F Wang Hai H Sun Wei W He Chengyan C

Frontiers in molecular biosciences 20250409

<h4>Background</h4>Acute coronary syndrome (ACS) is a cardiovascular disease caused by acute myocardial ischemia. The aim of this study was to use urine metabolomics to explore potential biomarkers for the diagnosis of ACS and the changes in metabolites during the development of this disease.<h4>Methods</h4>Urine samples were collected from 81 healthy controls and 130 ACS patients (103 UA and 27 AMI). Metabolomics based on liquid chromatography-mass spectrometry (LC-MS) was used to analyze urine ...[more]

PMID: 40270590

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