Proteomics

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Resveratrol exerts antiviral activity against pseudorabies virus through regulation of the OPN-ERK/JNK-IL-1β signaling axis


ABSTRACT: We analyzed the changes in the cellular proteome after PRV infection in resveratrol-treated PK-15 cells using TMT quantitative proteomics combined with LC-MS/MS. The results identified the differential proteins osteopontin (iOPN) and interleukin-1 receptor accessory protein (IL-1RAP), which have significant biological implications. The regulation of OPN-IL-1β signaling by PRV infection was further studied through the OPN-ERK/JNK-IL-1β signaling axis

ORGANISM(S): Suid Alphaherpesvirus 1

SUBMITTER: Xu Song  

PROVIDER: PXD060943 | iProX | Wed Feb 19 00:00:00 GMT 2025

REPOSITORIES: iProX

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