Proteomics

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Mass spectrometry analysis for IP with SNX10 Antibody in CRC HCT-8 cell

ABSTRACT: SNX10-HA overexpression was performed in CRC HCT-8 cells. Cells were then infected with HCoV-OC43 or control virus fluid. The protein interacted with SNX10 were analyzed by mass spectrometry. The SNX10 overexpressed and control cells in the logarithmic growth phase were collected for IP with HA-Tag Antibody.

ORGANISM(S): Homo Sapiens

SUBMITTER: Shuwen Liu  

PROVIDER: PXD061906 | iProX | Mon Mar 17 00:00:00 GMT 2025

REPOSITORIES: iProX

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Publications

SNX10 enhances HCoV-OC43 infection by facilitating viral entry and inhibiting virus-triggered autophagy.

Li Haobin H   Guo Huiyi H   Rong Binhao B   Li Haowei H   Wu Wenjiao W   Yang Chan C   Liu Shuwen S  

Virologica Sinica 20250709

The ongoing coronavirus epidemic, including the novel coronavirus (COVID-19), continues to pose a significant threat to global public health. Host targets address multiple stages of the viral life cycle and provide diverse opportunities for therapeutic interventions. This study identified sorting nexin 10 (SNX10) as a facilitator of replication of human coronavirus OC43 (HCoV-OC43), underscoring its potential as a novel antiviral target. The knockout of SNX10 significantly suppressed HCoV-OC43 r  ...[more]

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