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Proteomic profiling of the global protein changes of Neuro-2a cells treated with siFUS or control

ABSTRACT: We conducted unbiased mass spectrometric experiments to evaluate the specificity of siFUS. In these studies, Neuro-2a cells were treated with siFUS. The result revealed the detection of more than 5000 proteins, among which there was a notable degradation of FUS, confirming the targeted action of siFUS against FUS protein.

ORGANISM(S): Mus Musculus

SUBMITTER: Songbo Xie

PROVIDER: PXD062670 | iProX | Mon Apr 07 00:00:00 BST 2025

REPOSITORIES: iProX

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