Anti-Asthmatic Immune Mechanisms of the Mt.b ESAT6-Fc Fusion Protein Administered via Intranasal Immunization in Murine Allergic Asthma

ABSTRACT: ESAT6 is secreted by Mycobacterium tuberculosis and has anti-asthmatic properties. Administered via intranasal immunization, ESAT6-Fc fusion protein significantly alleviated in ovalbumin (OVA)-induced allergic asthma (AA) model mice. To investigate the underlying immune regulatory mechanisms of ESAT6 protein, integrated proteomics and transcriptomics analyses were conducted.

ORGANISM(S): Mus Musculus

SUBMITTER: Qiaofeng Wan  

PROVIDER: PXD062714 | iProX | Mon Apr 07 00:00:00 GMT+01:00 2025

REPOSITORIES: iProX