Proteins modified by succination

ABSTRACT: Fumarate accumulation during renal fibrosis may be involved in renal inflammation by conferring succination to certain proteins to influence intracellular signaling. We applied a Desthiobiotin-Iodoacetamide (DBIA) probe as a competitive probe for covalently labelling fumarate and combined with a liquid chromatography-tandem mass spectrometry (LC-MS/MS) platform to identify the modified proteins.

ORGANISM(S): Mus Musculus

SUBMITTER: Wei Wang  

PROVIDER: PXD063006 | iProX | Tue Apr 15 00:00:00 BST 2025

REPOSITORIES: iProX