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Plasma multi - omics profiling unravels molecular alterations and biomarker panels during recovery from severe coronavirus disease 2019

ABSTRACT: Plasma proteomic profiling on severe COVID - 19 patients at different stages. Revealed molecular alterations in inflammation and lipid metabolism during recovery. Identified a biomarker panel for prognosis prediction

ORGANISM(S): Homo Sapiens

SUBMITTER: Qian Wang

PROVIDER: PXD063087 | iProX | Fri Apr 18 00:00:00 BST 2025

REPOSITORIES: iProX

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Plasma multi-omics profiling unravels molecular alterations and biomarker panels during recovery from severe coronavirus disease 2019: a pilot study.

Wang Qian Q Wang Delong D Hu Xujuan X Long Gangyu G Tang Yun Y Ren Lehao L Fang Xiangzhi X Shang You Y Zhang Dingyu D Han Yang Y Gong Rui R

BMC infectious diseases 20260425 1

<h4>Background</h4>The potential multidimensional molecular alterations during recovery of severe patients with coronavirus infectious disease (COVID-19) remain to be elucidated. Early assessment of the prognosis of severe COVID-19 may facilitate appropriate medical interventions.<h4>Methods</h4>In this small-cohort exploratory study, plasma proteomic and widely targeted metabolomic profiling were conducted on 24 severe COVID-19 patients: 12 patients who underwent severe-to-mild transformation w ...[more]

PMID: 42034967

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