Ontology highlight
ABSTRACT:
ORGANISM(S): Oryza Sativa
SUBMITTER: Jianguo Wu
PROVIDER: PXD063713 | iProX | Wed May 07 00:00:00 BST 2025
REPOSITORIES: iProX
Zou Jing J Zhang Shuai S Chen Ying Y He Chun C Pan Xin X Zhang Yimin Y Xu Jianwei J Zheng Lijia L Guan Hongxin H Wu Ming M Xie Dongqi D Ji Yinghua Y Fang Xianyang X Li Yi Y Ding Shou-Wei SW Fang Xiaofeng X Zhao Shanshan S Wu Jianguo J
Nature communications 20250704 1
Liquid-liquid phase separation (LLPS) regulates diverse biological functions by mediating the assembly of biomolecular condensates. However, it remains unclear how host LLPS is targeted by viruses during infection. Here we show that a plant bunyaviral protein, the disease-specific protein (SP) encoded by rice stripe virus (RSV), possesses phase separation potential through its N-terminal intrinsically disordered region 1 (IDR1). In vivo, however, SP does not form phase-separated biomolecular con ...[more]