Proteomics

Dataset Information

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Act1 disrupts SHP2 stability by shifting the pyroglutamylation-ubiquitination balance to inhibit tumor progression


ABSTRACT: SHP2 stability is regulated by the dynamic antagonism of pyroglutamylation and ubiquitination, with Act1 influencing this balance, impacting cancer progression and therapy.

ORGANISM(S): Homo Sapiens

SUBMITTER: Qiong Luo  

PROVIDER: PXD064284 | iProX | Fri May 23 00:00:00 BST 2025

REPOSITORIES: iProX

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