Nanoliposuction recycles senescent cell lipids for lubrication

ABSTRACT: This study aims to systematically profile membrane protein alterations associated with chondrocyte senescence, in order to identify surface markers specifically upregulated in aged cartilage. We established two in vitro models by treating primary chondrocytes with IL-1β or bleomycin, and one in vivo model by comparing cartilage from young and aged mice. Membrane proteins were extracted and subjected to quantitative proteomic analysis.

ORGANISM(S): Mus Musculus

SUBMITTER: Yiying Qi  

PROVIDER: PXD064867 | iProX | Tue Jun 10 00:00:00 GMT+01:00 2025

REPOSITORIES: iProX