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Multi-omics profiling of Parkinson’s disease mouse models reveals region-specific molecular alterations

ABSTRACT: We conducted proteomic and phosphoproteomic profiling of two widely used Parkinson’s disease (PD) mouse models: the neurotoxin-based MPTP model and the α-synuclein preformed fibril (PFF) inoculation model. Tissues from substantia nigra and cerebellum were collected for multi-omics analysis to uncover region-specific protein expression and phosphorylation changes associated with PD pathogenesis.

ORGANISM(S): Mus Musculus

SUBMITTER: Yu Xue

PROVIDER: PXD065072 | iProX | Mon Jun 16 00:00:00 BST 2025

REPOSITORIES: iProX

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