Proteomics

Dataset Information

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The mass spectrometry data for the identification of eNOS-binding protein


ABSTRACT: The activity of endothelial nitric oxide synthase (eNOS) is regulated through intricate crosstalk among transcriptional, post-transcriptional, and post-translational modalities. Translational modification cascades and their downstream signaling relay emerge as pivotal controllers of both eNOS functionality and nitric oxide bioavailability, positioning these pathways as prime therapeutic targets. A deeper elucidation of the molecular machinery governing post-translational regulation of eNOS holds promise for developing innovative approaches to forestall endothelial dysfunction and its consequent hypertensive complications.

ORGANISM(S): Homo Sapiens

SUBMITTER: Sijia Liang  

PROVIDER: PXD066908 | iProX | Sun Aug 03 00:00:00 BST 2025

REPOSITORIES: iProX

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