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Proximity labeling of Nup96 and HOS1 revealed a network of proteins in stress response

ABSTRACT: The Y-complex, an essential peripheral component of the nuclear pore complex (NPC), plays crucial roles in nucleocytoplasmic transport, mRNA surveillance and transport, chromatin organization, and gene expression regulation. In plants, the Y-complex nucleoporins Nup96 and HOS1 are critical for modulating salt stress responses, flowering time, thermotolerance, salinity-delayed flowering, miRNA biogenesis, and hypocotyl growth. However, the regulatory mechanisms of the plant Y-complex remain largely unknown. Using proximity labeling technology, we identified several proteins labeled by Nup96 and HOS1, which will facilitate further investigation into the functions of the Y-complex in regulating these biological processes.

ORGANISM(S): Arabidopsis Thaliana

SUBMITTER: Yu Tang

PROVIDER: PXD068406 | iProX | Mon Sep 15 00:00:00 BST 2025

REPOSITORIES: iProX

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