Colon-Targeted Astragalus Polysaccharide Nanoparticles Prevent NAFLD-Driven Hepatocarcinogenesis via Microbiota Remodeling and NF-κB Inhibition
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ABSTRACT: This study aimed to explore the mechanism of Astragalus Polysaccharide loaded chitosan / pectin nanoparticles (APS CS / Pt NPs) in preventing the malignant transformation of liver fibrosis to liver cancer by regulating the gut liver axis, improving the structure of intestinal flora, reducing lipid accumulation, and regulating the nf- κ B signaling pathway.
ORGANISM(S): Mus Musculus
SUBMITTER:
Yang Sun
PROVIDER: PXD068506 | iProX | Wed Sep 17 00:00:00 BST 2025
REPOSITORIES: iProX
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