Proteomics

Dataset Information

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Mice osteoclast-derived apoptotic bodies LC-MS/MS


ABSTRACT: We design OsteoSAVE, a peptide-based nanoparticle integrating a cathepsin K (CTSK)-cleavable linker, a bone-targeting motif, and a self-assembling biphenyl core. Upon CTSK-mediated hydrolysis, OsteoSAVE transforms into nanofibers within osteoclast lysosomes, inducing apoptosis and releasing apoptotic bodies.

ORGANISM(S): Mus Musculus

SUBMITTER: Huaimin Wang  

PROVIDER: PXD069800 | iProX | Wed Oct 22 00:00:00 BST 2025

REPOSITORIES: iProX

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