Cryo-EM Structures of Biopsy-derived TTR Filaments in Hereditary Transthyretin Amyloidosis.

ABSTRACT: We examined the structure of transthyretin filaments extracted from the vitreous humor of an individual with ATTRv-F64S by cryo-electron microscopy. Mass spectrometry was used to confirmed the presence of both mutant and wild-type transthyretin in the filaments.

ORGANISM(S): Homo Sapiens

SUBMITTER: Yang Shi  

PROVIDER: PXD070068 | iProX | Thu Oct 30 00:00:00 GMT 2025

REPOSITORIES: iProX