Proteomics

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Lipid Droplet–Mediated Depletion of DAG in the TGN Impairs IFNGR1 Membrane Localization and Anti-Tumor Immunity


ABSTRACT: Lipid droplets (LDs) are dynamic organelles that regulate cellular metabolism, yet their role in tumor immune evasion remains unclear. Here, we demonstrate that LDs in cancer cells suppress anti-tumor immunity by impairing the membrane location of interferon-gamma receptor 1 (IFNGR1).

ORGANISM(S): Homo Sapiens

SUBMITTER: Yanhong Gu  

PROVIDER: PXD070259 | iProX | Mon Nov 03 00:00:00 GMT 2025

REPOSITORIES: iProX

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