Proteomics

Dataset Information

0

Plasma Multi-Omics in Response to Long-Term Low-Dose Ionizing Radiation


ABSTRACT: This study performed quantitative plasma proteomics on 5 radiation-exposed workers and 5 healthy controls using high-resolution LC-MS/MS (Orbitrap Exploris 480). Proteins were extracted, reduced, alkylated, trypsin-digested, and analyzed in DDA mode. Data was processed with Spectronaut 14 using dynamic iRT prediction, 1% FDR filtering, and top3 peptide quantification. Differentially expressed proteins between groups were identified using Welch's ANOVA (p<0.05, FC>1.5) to investigate the impact of occupational radiation exposure.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xinjun Wang  

PROVIDER: PXD070331 | iProX | Wed Nov 05 00:00:00 GMT 2025

REPOSITORIES: iProX

Similar Datasets

2022-04-07 | MTBLS3854 | MetaboLights
2015-03-31 | GSE67309 | GEO
2023-04-18 | PXD041320 | Pride
2015-03-31 | E-GEOD-67309 | biostudies-arrayexpress
2014-12-01 | GSE62662 | GEO
2009-05-31 | GSE14466 | GEO
2016-01-01 | GSE64375 | GEO
2017-12-01 | GSE63952 | GEO
2024-04-05 | PXD048318 | Pride
2023-04-07 | GSE228572 | GEO