A Dual-Module ECAS Complex Integrates Transcription Elongation and RNA Processing

ABSTRACT: ECAS is a bipartite complex that links RNA polymerase II elongation with co-transcriptional RNA processing. It acts independently of P-TEFb, supports elongation, splicing, and 5' capping, and prevents premature termination. Disruption of ECAS impairs transcript elongation and splicing fidelity.

ORGANISM(S): Homo Sapiens

SUBMITTER: Kaiwei Liang  

PROVIDER: PXD070810 | iProX | Sat Nov 15 00:00:00 GMT 2025

REPOSITORIES: iProX