Project description:EBV encodes 44 mature miRNAs, a number of which have been found to promote carcinogenesis by targeting host genes. To determine the biological functions of the BART cluster miRNAs, we singly transfected these miRNAs into HEK293T cells. Interestingly, we found that overexpression of EBV-miR-BART6-3p in HEK293T cells dramatically altered HEK293T cell shape. To explore the mechanism of EBV-miR-BART6-3p-mediated inhibition of cell migration and invasion, we attempted to identify its downstream host cellular genes by whole genome microarray, which contains probes to all known human protein coding genes (mRNAs) and long non-coding RNA genes (lncRNAs).

2017-02-09 | GSE81528 | GEO

Basal Gene Expression Measurements in HEK293T Cells

Project description:Gene expression microarray profile for human embryonic kidney cells (HEK293T, CRL-11268) under untreated conditions. Gene expression microarray profile for human embryonic kidney cells (HEK293T, CRL-11268) under untreated conditions (DMEM, 10% FBS).

2010-04-12 | E-GEOD-21092 | biostudies-arrayexpress

Transcriptome analyses of bEV treated HEK293T cells

Project description:To get insight of molecular effects of bEV on HEK293T cells, we investigated transcriptomic response in bEV treated HEK293T cells We identified differentially expressed genes (DEGs) fold change cutoff = 1.5 in the bEV treated HEK293T cells These findings suggest that bEV would be putative ingredients by modulating signaling pathways in human cells

2025-07-12 | GSE270805 | GEO

Transcriptome-wide mapping of RNA:protein interactions of USP39 in HEK293T cells

Project description:Transcriptome-wide mapping of RNA:protein interactions of USP39 in HEK293T cells

| PRJNA954017 | ENA