Myeloid-Driven Inflammation Highlights ADGRE2 as a Biomarker in Prurigo Nodularis: Integrated Multi-Omics Analysis
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Juan Tao
PROVIDER: PXD072618 | iProX | Sun Jan 04 00:00:00 GMT 2026
REPOSITORIES: iProX
Publications
Myeloid-driven inflammation highlights ADGRE2 as a biomarker in prurigo nodularis: Integrated multiomics analysis.
He Ting T Wang Yifei Y Yu Guoqun G Dong Enzhu E Shen Chen C Tao Juan J
The Journal of investigative dermatology 20260115
Prurigo nodularis (PN) is a chronic pruritic skin disease characterized by hyperkeratotic nodules and intense itching, yet its pathological mechanisms remain unclear, especially at the protein level and in comparison with atopic dermatitis. We performed parallel analyses of proteomic data (4-dimensional data-independent acquisition) from lesions of PN, atopic dermatitis, and healthy controls. Single-cell RNA-sequencing data were integrated from publicly available datasets (eg, GSE222840) represe ...[more]
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