Proteomics

Dataset Information

0

Transgenic hookworm secretes anti-tetrodotoxin human single chain antibody


ABSTRACT: We generated transgenic hookworms secreting anti-TTX countermeasure s16-HuScFv. Proteomics samples were generated from host hamster serum

ORGANISM(S): Ancylostoma Ceylanicum Mesocricetus Auratus

SUBMITTER: Makedonka Mitreva  

PROVIDER: PXD073224 | iProX | Sat Jan 17 00:00:00 GMT 2026

REPOSITORIES: iProX

altmetric image

Publications


Biologics, protein- and peptide-based drugs derived from living organisms or cell lines have emerged as effective therapies across a broad range of indications. However, parenteral administration and the need for frequent dosing increase costs and limit compliance, creating an urgent need for innovative platforms capable of continuously, safely, and efficiently delivering sustained biologics in situ within the host. Here, we describe a bioengineered hookworm platform to manufacture and deliver b  ...[more]

Similar Datasets

| S-EPMC5573885 | biostudies-literature
2025-12-08 | PXD070488 | Pride
| S-EPMC4792179 | biostudies-literature
| S-EPMC8690526 | biostudies-literature
| S-EPMC3787825 | biostudies-literature
| S-EPMC6544282 | biostudies-literature
2023-01-30 | E-MTAB-12297 | biostudies-arrayexpress
2021-01-01 | GSE154564 | GEO