SC-43 Inhibits Methicillin-resistant Staphylococcus aureus Through Inhibition of Heme Biosynthesis

ABSTRACT: SC-43 inhibits the key enzyme coproporphyrin ferrochelatase (CpfC) of the coproporphyrin-dependent (CPD) heme synthesis pathway and interferes with the bacterial porphyrin metabolism.

ORGANISM(S): Staphylococcus Aureus

SUBMITTER: Wei Huang  

PROVIDER: PXD073397 | iProX | Thu Jan 22 00:00:00 GMT 2026

REPOSITORIES: iProX