Cytoplasmic ATRIP recuitment to centrosome
Ontology highlight
ABSTRACT: We fund that ATRIP was recruited to centrosomes, which mediated the hyperactivated centrosome maturation. Thus, to identify the centrosomal protein responsible for ATRIP centrosomal localization, we immunoprecipitated cytoplasmic ATRIP from G2-phase HeLa cells and analyzed the interactors by mass spectrometry. By disrupting ATRIP interactor, this aberrant process might be rescued, offering a potential therapy strategy.
ORGANISM(S): Homo Sapiens
SUBMITTER:
Xuefeng Chen
PROVIDER: PXD073837 | iProX | Fri Jan 30 00:00:00 GMT 2026
REPOSITORIES: iProX
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