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Chloroplast Nanotechnology for General Health

ABSTRACT: Chloroplast Nanotechnology for General Health using Omics analysis

ORGANISM(S): Spinacia Oleracea

SUBMITTER: David Tai Leong

PROVIDER: PXD076001 | iProX | Sat Mar 21 00:00:00 GMT 2026

REPOSITORIES: iProX

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Transplanting light-dependent reactions for mammalian eye photosynthesis.

Xing Kuoran K Yan Yan Y Zhu Ziyu Z Chen Yinglu Y Dadol Glebert Cañete GC Pan Xiangji X Tong Siye S Sikdar Narattam N Wang Jinping J Li Banglin B Yu Mengfei M Jin Kai K Ding Xianguang X Sun Xiao X Ye Juan J Leong David Tai DT

Cell 20260515

Mammalian eyes are exposed to visible light but cannot perform photosynthesis. Here, we show that introducing a nanoscale, structurally and functionally preserved thylakoid system, LEAF (light-reaction enriched thylakoid NADPH-foundry), into corneal cells enables light-driven bona fide photosynthetic production of NADPH and ATP, similar to plant leaves, which alleviates oxidative stress and inflammation. LEAF acts in two domains. Intracellularly, it integrates with host cells to supply NADPH and ...[more]

PMID: 42143020

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