Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Extracellular proteomic analysis of WAS

ABSTRACT: Extracellular proteomic analysis of residual sludge

ORGANISM(S): Environmental Samples <ascomycetes,capnodiales Incertae Sedis>

SUBMITTER: Fang Zhang

PROVIDER: PXD077361 | iProX | Fri Apr 17 00:00:00 BST 2026

REPOSITORIES: iProX

ACCESS DATA

Json Xml

Similar Datasets

Time-series proteomic analysis of body fluid extracellular vesicles in amyotrophic lateral sclerosis

Project description:Time-series proteomic analysis of body fluid extracellular vesicles in amyotrophic lateral sclerosis

| PRJNA1015658 | ENA

Cerebrospinal fluid-derived extracellular vesicles: a proteomic and transcriptomics comparative analysis of enrichment protocols

Project description:Cerebrospinal fluid-derived extracellular vesicles: a proteomic and transcriptomics comparative analysis of enrichment protocols

| PRJNA1281578 | ENA

Systemic proteomic and small RNA profile analysis of extracellular vesicles derived from Theileria annulata

Project description:Systemic proteomic and small RNA profile analysis of extracellular vesicles derived from Theileria annulata

| PRJNA1175652 | ENA

Secretome of Bone Marrow Stroma-Derived Neural Progenitor Cells: Proteomic Analysis

Project description:We found the bone marrow stromal-derived neural progenitor cells secretome have the neural protection effect. Proteomic analysis was performed nn order to analyze the protection factor in the secretome. Keywords: Neural protection, secretome

2008-10-18 | GSE13242 | GEO

Proteomic signatures of extracellular vesicles secreted by non-mineralizing and mineralizing human osteoblasts and stimulation of tumor cell growth

Project description:Beyond forming bone, osteoblasts play pivotal roles in various biological processes, including hematopoiesis and bone metastasis. Extracellular vesicles (EVs) have recently been implicated in intercellular communication via transfer of proteins and nucleic acids between cells. Here, we focused on the proteomic characterization of non-mineralizing (NMOBs) and mineralizing (MOBs) human osteoblast (SV-HFOs) EVs and investigated their effect on human prostate cancer (PC3) cells by microscopic, proteomic and gene expression analyses. Proteomic analysis showed that 97% of the proteins were shared among NMOB and MOB EVs, and 30% were novel osteoblast-specific EV proteins. Label-free quantification demonstrated mineralization stage-dependent five-fold enrichment of 59 and 451 EV proteins in NMOBs and MOBs, respectively. Interestingly, bioinformatic analyses of the osteoblast EV proteomes and EV-regulated prostate cancer gene expression profiles showed that they converged on pathways involved in cell survival and growth. This was verified by in vitro proliferation assays where osteoblast EV uptake led to two-fold increase in PC3 cell growth compared to cell-free culture medium-derived vesicle controls. Our findings elucidate the mineralization stage-specific protein content of osteoblast-secreted EVs, show a novel way by which osteoblasts communicate with prostate cancer, and open up innovative avenues for therapeutic intervention. PC3 cells were treated with extracellular vesicles from non-mineralizing and mineralizing SV-HFOs for three different incubation times (4hrs, 24hrs, 48hr)

2014-10-28 | E-GEOD-56172 | biostudies-arrayexpress

Clinical Proteomic Tumor Analysis Consortium (CPTAC)

Project description:Clinical Proteomic Tumor Analysis Consortium (CPTAC)

| PRJNA371289 | ENA

Proteomic

Project description:Proteomic

2022-12-31 | OEX00021177 | NODE

Deep proteomic analysis of murine erythroid differentiation

Project description:Deep proteomic analysis of murine erythroid differentiation

| PRJNA492908 | ENA

Systemic proteomic and small RNA profile analysis of extracellular vesicles derived from Theileria annulata

Project description:Extracellular vesicles (EVs) are key mediators of intercellular communication, and often play critical roles in host-parasite interactions by facilitating parasite’s physiology and pathogenesis. Theileria annulata, an apicomplexan parasite, induces profound changes in host cells, leading to uncontrolled proliferation, apoptosis resistance, and increased invasiveness. In this study, we performed the comprehensive proteomic and small RNA analysis of EVs isolated from a T. annulata Kashi isolate-infected bovine lymphocyte cell line (TaXJS), B cell line (TaBC), dendritic cell line (TaDC), and from the sera of cattle before and after infection. Our label-free LC-MS/MS proteomics identified 2580 proteins, while small RNA sequencing revealed 6635 miRNAs associated with parasite development, host invasion, and immune evasion. Functional enrichment analyses recognized vesicular components involved in key pathways of the parasite-host such as ECM-receptor interaction, oxidative phosphorylation, and proton transport. These findings highlight the potential of Theileria-derived EVs in modulating host responses and their potential as therapeutic and vaccine targets.

2025-10-21 | GSE279977 | GEO

Alterations to the Hidradenitis Suppurativa Serum Proteome with Spleen Tyrosine Kinase Antagonism: Proteomic Results from a Phase 2 Clinical Trial.

Project description:Serum Proteomic Analysis of patients with Hidradenitis Suppurativa treated with Fostamatinib

2023-08-10 | GSE240607 | GEO