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Ntegrated Analysis of Gut Microbiota, Serum Metabolomics, and Proteomics Reveals Novel Associations With Clinical Symptoms in Patients With Cerebral Infarction

ABSTRACT: A total of 20 CI patients and 20 healthy controls (HC) were enrolled. Fecal microbiota was profiled using 16S rRNA gene high-throughput sequencing. Serum metabolomics and proteomics were analyzed using ultra-high-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and data-independent acquisition (DIA) proteomics, respectively. Spearman correlation and multi-omics integration were applied to explore the associations among microbiota, metabolites, proteins, and clinical indicators.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xingbang Wang

PROVIDER: PXD077506 | iProX | Thu Apr 23 00:00:00 BST 2026

REPOSITORIES: iProX

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